Ringdal G I, Ringdal K, Kvinnsland S, Götestam K G
University of Trondheim, Faculty of Medicine, Department of Psychiatry, Norway.
Qual Life Res. 1994 Apr;3(2):143-54. doi: 10.1007/BF00435257.
This study examines differences and similarities in the quality of life of 253 cancer patients with good, medium and poor prognoses. Our main hypothesis was that patients with a good prognosis will experience a higher quality of life than patients with a medium or poor prognosis. A multivariate analysis of covariance of eight quality of life scales was performed with prognosis as a factor and with age, sex, and the duration of the illness as covariates. Significant main effects of prognosis were found for the general QOL-scale and for physical aspects of quality of life. There were, however, only marginal and non-significant effects of prognosis groups on social and psychological functioning. A final multivariate analysis confirms earlier findings that performance status shows a weak but significant relationship with the psychological functioning. Thus, the physical condition of the patient at the time of measurement seems to have some influence on the psychological functioning, whereas the severity of the disease as indicated by the classification into prognosis groups does not. These results question the general attitude that seriously ill cancer patients have reduced social and psychological well-being. An alternative interpretation is that the scales used to measure psychological aspects of quality of life are inadequately sensitive.
本研究调查了253名预后良好、中等和较差的癌症患者在生活质量方面的差异与相似之处。我们的主要假设是，预后良好的患者比预后中等或较差的患者生活质量更高。以预后为因素，年龄、性别和病程为协变量，对八个生活质量量表进行了多变量协方差分析。在总体生活质量量表和生活质量的身体方面发现了预后的显著主效应。然而，预后组对社会和心理功能仅有微弱且不显著的影响。最终的多变量分析证实了早期的研究结果，即表现状态与心理功能呈微弱但显著的关系。因此，测量时患者的身体状况似乎对心理功能有一定影响，而根据预后分组所表明的疾病严重程度则没有影响。这些结果对重病癌症患者社会和心理健康状况下降的普遍看法提出了质疑。另一种解释是，用于测量生活质量心理方面的量表敏感性不足。
