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交叉性失语一例中言语和非言语功能的恢复及变化模式:对功能性脑侧化和定位模型的启示

Patterns of recovery and change in verbal and nonverbal functions in a case of crossed aphasia: implications for models of functional brain lateralization and localization.

作者信息

Trojano L, Balbi P, Russo G, Elefante R

机构信息

Clinica del Lavoro Foundation, IRCCS, Medical Center of Rehabilitation, Campoli Monte Taburno, Italy.

出版信息

Brain Lang. 1994 May;46(4):637-61. doi: 10.1006/brln.1994.1035.

Abstract

We present a 2-year verbal and nonverbal follow-up of a crossed aphasic patient. The patient had suffered from widespread ischemic damage in the area of right middle cerebral artery, with a parieto-temporal lesion. Three months postonset he showed classical Wernicke's aphasia associated with oral, limb and constructional apraxia and left hemineglect. However, follow-up findings showed a complex, dynamic pattern entirely consistent with cognitive models of language and nonlanguage abilities. Current models of functional brain lateralizations could not satisfactorily account for such longitudinal, fine-grain observations.

摘要

我们对一名交叉性失语患者进行了为期两年的言语和非言语随访。该患者右侧大脑中动脉区域遭受广泛缺血性损伤,伴有顶颞叶病变。发病三个月后,他表现出典型的韦尼克失语症,伴有口部、肢体和结构性失用症以及左侧半侧空间忽视。然而,随访结果显示出一种复杂的动态模式,与语言和非语言能力的认知模型完全一致。目前的功能性脑侧化模型无法令人满意地解释这种纵向的、细粒度的观察结果。

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