Some aspects of erythropoietic cell proliferation in erythroleukaemia.

Cytophotometric-autoradiographic investigations on erythropoiesis in erythroleukaemia indicate (1) the decreased labelling index of erythroblasts is explained by an increased percentage of these cells in G-i; (2) 'megaloblastoid' basophilic erythroblasts show a more pronounced decrease of their fraction in DNA synthesis than morphological normal cells; (3) 'megaloblastoid' early polychromatic normoblasts represent a non-proliferating cell population, and (4) the detected disturbance of cell proliferation - even though temporary - can be reversed.