[D-葡萄糖醛酸对细胞毒性骨髓抑制中骨髓粒单核细胞生成过程刺激作用的机制]
[Mechanisms of the stimulating effect of d-glucuronic acid on the processes of bone marrow granulomonocytopoiesis in cytostatic myelodepression].
作者信息
Gol'dberg E D, Dygaĭ A M, Karpova G V, Simanina E V, Khlusov I A, Shakhov V P, Agafonov V I
出版信息
Biull Eksp Biol Med. 1993 Apr;115(4):350-2.
The mechanisms of regulating influence of D-glucuronic acid on granulomonocytopoiesis++ have been studied by using the model of cyclophosphamide-induced myelodepression. Increase of colony-stimulating and interleukin-1 activities production by hemopoiesis inducing microenvironment cells, the stimulation of hemopoietic islets and the different granulomonocytopoiesis precursor cells forming have been shown to be the base of activating action of D-glucuronic acid on bone marrow granulomonocytopoiesis recovery.
利用环磷酰胺诱导骨髓抑制模型，研究了D-葡萄糖醛酸对粒细胞单核细胞生成的调节影响机制。造血诱导微环境细胞的集落刺激活性和白细胞介素-1活性产生增加、造血岛的刺激以及不同粒细胞单核细胞生成前体细胞的形成，已被证明是D-葡萄糖醛酸对骨髓粒细胞单核细胞生成恢复的激活作用的基础。
Zotero 插件