Oláh I, Glick B
2nd Department of Anatomy, Semmelweis Medical School, Budapest, Hungary.
Dev Comp Immunol. 1994 Jan-Feb;18(1):67-73. doi: 10.1016/0145-305x(94)90253-4.
Splenic stromal cells were studied with anti-vimentin monoclonal antibody clones V9 and 3B4. V9 positive cells were widely distributed both in the red and white pulp, specifically the ellipsoid, but were absent from the germinal centers. These observations suggested that this clone recognized splenic reticular cells. The original name given to the splenic ellipsoid region by Schweigger-Seidel, "Kapillarhülse" or capillary sleeve, would be a more appropriate term than ellipsoid, at least in the chicken because the V9 positive ellipsoid covered the entire length of the penicilliform capillary. The capillary sleeve was decorated by large, 3B4 positive cells that were identical to the ellipsoid-associated cells, a dendritic-like cell. The 3B4 monoclonal antibody recognized large stellate-shaped cells in germinal centers. These data emphasized the cellular difference between ellipsoid-associated cells and the cells of the ellipsoid; the cytoskeletal similarities of the ellipsoid-associated cells and dendritic cells of germinal centers advocate their common cell lineage.
用抗波形蛋白单克隆抗体克隆V9和3B4对脾基质细胞进行了研究。V9阳性细胞广泛分布于红髓和白髓，特别是椭圆体，但生发中心没有。这些观察结果表明，该克隆识别脾网状细胞。施魏格-赛德尔最初给脾椭圆体区域起的名字“Kapillarhülse”或毛细血管套，至少在鸡身上，比椭圆体更合适，因为V9阳性的椭圆体覆盖了笔形毛细血管的全长。毛细血管套由与椭圆体相关细胞相同的大型3B4阳性细胞修饰，这是一种树突状细胞。3B4单克隆抗体识别生发中心的大型星状细胞。这些数据强调了椭圆体相关细胞与椭圆体细胞之间的细胞差异；椭圆体相关细胞与生发中心树突状细胞的细胞骨架相似性表明它们有共同的细胞谱系。
