Kolster J, Martí A, Castro de Kolster C, Fonseca A
Departamento de Medicina, Universidad de Carababo.
G E N. 1993 Oct-Dec;47(4):204-8.
In 1991, we report drug interactions found through the review of 100 clinical charts of an Emergency Department. Two years later we evaluated again the medical indications done at the same Emergency. There were no differences related to sex, age and number of drug administrated by patient when compared with the former group. There was, however, a significant decrease in the percentage of interactions and those important ones. Also, in the average of interactions and those important ones by patient. Among more used drug, antacid occupied a a second place with 36% and Ranitidine the ninth place with 16%. Cimetidine disappeared among the first ten medications. In those cases where antacid or Ranitidine were indicated, there were interactions in 54% and 25%, respectively, but these interactions were not significant. The results of this new analysis point out a significant decrease of drug interactions, showing that continuing education allows indicate the most adequate therapy to each patient.
1991年，我们报告了通过回顾某急诊科100份临床病历发现的药物相互作用情况。两年后，我们再次评估了同一急诊科的用药指征。与前一组相比，在性别、年龄和患者用药数量方面没有差异。然而，相互作用以及重要相互作用的百分比显著下降。此外，患者的平均相互作用以及重要相互作用数量也有所下降。在使用较多的药物中，抗酸剂以36%位居第二，雷尼替丁以16%位居第九。西咪替丁在前十大药物中消失。在使用抗酸剂或雷尼替丁的病例中，分别有54%和25%存在相互作用，但这些相互作用并不显著。这项新分析的结果表明药物相互作用显著减少，表明继续教育有助于为每位患者指明最适当的治疗方法。
