The role of diet cholesterol changes on EEG.

Thirty three male albino rats, weight between 200 and 220 g were used in this experiment. Control animals consisting of 11 rats were fed with a normal lab diet for a period of 14 weeks and the others (22) were fed with a diet containing 1% cholesterol for the same period. At the end of the experimental period, plasma cholesterol level (Mean +/- SD) was 141.29 +/- 34.5 mg/dl in the cholesterol group and 70.66 +/- 10 mg/dl in the control group. Eleven of the rats from the cholesterol group were transferred to the normal diet for 14 weeks (normocholesterolemic group). Spectral analysis of EEG records from parietal lobes of animals showed that there was an obvious depression in the brain waves of hypercholesterolemic rats whereas no depression in normocholesterolemic rats.