富含胆固醇大鼠的SEP频谱分析。

SEP spectral analysis of cholesterol rich rats.

作者信息

Yargiçoğlu P, Ağar A, Taymaz A, Oğuz Y, Oner G

机构信息

Department of Biophysics & Physiology, Faculty of Medicine, Akdeniz University, Antalya, Turkey.

出版信息

Int J Neurosci. 1993 Feb;68(3-4):273-81. doi: 10.3109/00207459308994282.

DOI:10.3109/00207459308994282

PMID:8063532

Abstract

In this study, twenty four albino rats, weighing between 180 and 200 g were tested. One half was fed with a diet containing 1% cholesterol for 12 weeks and the other half was fed with a normal lab diet for the same period. After the experimental period, the plasma cholesterol level in the diet group was 134.04 +/- 21.11 mg/dl compared with the control group 72.72 +/- 10.5 mg/dl. In the two groups, SEPs were recorded from central (Cz) referenced to frontal (Fz) following left posterior tibial nerve (PTN) stimulation. Amplitude spectra of SEPs were computed by Fast Fourier Transform (FFT) algorithm. Their amplitude maxima were found to occupy the frequency bands of 1-3.5, 4-5, 6-7, 8-10, 11-12, 13-20, 20.5-36 and 36 Hz and above. The decibel (dB) values of the maxima were statistically lower for hypercholesterolemia than for the normals in the all the frequency bands.

摘要

在本研究中，对24只体重在180至200克之间的白化病大鼠进行了测试。其中一半喂食含1%胆固醇的饮食12周，另一半在同一时期喂食正常实验室饮食。实验期结束后，饮食组的血浆胆固醇水平为134.04 +/- 21.11毫克/分升，而对照组为72.72 +/- 10.5毫克/分升。在两组中，在刺激左侧胫后神经（PTN）后，从以额部（Fz）为参考的中央（Cz）记录体感诱发电位（SEP）。通过快速傅里叶变换（FFT）算法计算SEP的振幅谱。发现它们的最大振幅占据1 - 3.5、4 - 5、6 - 7、8 - 10、11 - 12、13 - 20、20.5 - 36和36赫兹及以上的频段。在所有频段中，高胆固醇血症组的最大分贝（dB）值在统计学上低于正常组。