Shaffer M F, Peirce W A, Lislie G A
J Infect Dis. 1975 Mar;131(3):277-80. doi: 10.1093/infdis/131.3.277.
Chicks were given intracerebral inoculations of Neisseria gonorrhoeae of colony types 1 or 2 one to two days after hatching. Small numbers ofN. gonorrhoeae initiated lethal infection provided that the body temperature of the animals was not maintained at levels harmful to the microbes per se. The disease process, which appeared to be localized intracranially rather than disseminated by bacteremia, merits further investigation as a model for the study of pathogenetic and immunologic mechanisms in gonococcal infection.
雏鸡在孵化后1至2天接受1型或2型菌落的淋病奈瑟菌脑内接种。只要动物的体温不维持在对微生物本身有害的水平，少量淋病奈瑟菌就能引发致命感染。该疾病过程似乎局限于颅内，而非通过菌血症传播，作为研究淋球菌感染的发病机制和免疫机制的模型，值得进一步研究。
