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小鼠脑内淋病奈瑟菌感染。

A mouse intracerebral infection with Neisseria gonorrhoeae.

作者信息

Diena B B, Ryan A, Ashton F E, Wallace R, Perry M B, Daoust V

出版信息

Br J Vener Dis. 1975 Feb;51(1):22-4. doi: 10.1136/sti.51.1.22.

Abstract

An intracerebral challenge of HPB black mice with Neisseria gonorrhoeae is described. In this mode, the mice died from 1 to 6 days after challenge, and T1 organisms were obtained up to the fifth day from brain, liver, kidney, and spleen. Experimental gonococcal vaccines gave good protection against the challenge.

摘要

描述了用淋病奈瑟菌对HPB黑色小鼠进行脑内攻击的实验。在这种实验模式下,小鼠在攻击后1至6天内死亡,直到第5天,在脑、肝、肾和脾中均能分离出T1菌株。实验性淋球菌疫苗对该攻击具有良好的保护作用。

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