Partonen T, Partinen M
Ullanlinna Sleep Disorders Clinic and Research Centre, Helsinki, Finland.
Acta Psychiatr Scand Suppl. 1994;377:41-5. doi: 10.1111/j.1600-0447.1994.tb05801.x.
The concept of seasonal affective disorder (SAD) includes any depression whose onset is related to a certain season. Reduced environmental light is hypothesized to be the main precipitating factor of winter depression. Light treatment is used to prevent the onset of depressive episodes and to reduce depressive symptoms in patients with depression during winter months. The mechanisms of action which lead to the well-documented antidepressant response are still unknown. Several hypotheses of the pathogenesis of SAD are discussed, and the clinical practice of light treatment is reviewed.
季节性情感障碍(SAD)的概念包括任何发病与特定季节相关的抑郁症。环境光照减少被认为是冬季抑郁症的主要诱发因素。光疗法用于预防抑郁发作,并减轻冬季抑郁症患者的抑郁症状。导致有充分记录的抗抑郁反应的作用机制仍不清楚。本文讨论了SAD发病机制的几种假说,并对光疗法的临床实践进行了综述。