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部分杏仁核损伤大鼠的应激后镇痛

Post-stress analgesia in rats with partial amygdala lesions.

作者信息

Werka T

机构信息

Department of Neurophysiology, Nencki Institute of Experimental Biology, Warsaw, Poland.

出版信息

Acta Neurobiol Exp (Wars). 1994;54(2):127-32.

PMID:8053408
Abstract

The role of the dorsal basal and the central nuclei of the amygdala under two modes of foot-shock analgesia was studied in 45 Möll-Wistar rats. Four minutes of continuous foot-shock produced post-stress analgesia in control and in all lesioned rats, but 20 min of regularly intermittent foot-shock did not evoke analgesia in rats with central nucleus lesion. This result indicates different involvement of dorsal basal and central nuclei in processing of stressful stimuli.

摘要

在45只莫尔-威斯塔大鼠中研究了杏仁核背侧基底核和中央核在两种足部电击镇痛模式下的作用。持续4分钟的足部电击在对照组和所有损伤大鼠中均产生了应激后镇痛，但20分钟的定期间歇性足部电击在中央核损伤的大鼠中未诱发镇痛。这一结果表明背侧基底核和中央核在应激刺激处理过程中的参与情况不同。

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