Marttila O, Jaakkola J J, Vilkka V, Jäppinen P, Haahtela T
South Karelia Allergy and Environment Institute, Tiuruniemi, Finland.
Environ Res. 1994 Aug;66(2):152-9. doi: 10.1006/enrs.1994.1051.
We assessed the role of long-term exposure to ambient air malodorous sulfur compounds released from pulp mills as a determinant of eye and respiratory symptoms and headache in children. Adverse health effects of environmental exposure to these compounds in children have not been reported previously. The parents of 134 children living in a severely polluted (n = 42), moderately polluted (n = 62) and rural nonpolluted (n = 30) community responded to a cross-sectional questionnaire. The response rate was 83%. The adjusted odds ratios (OR) for symptoms experienced during the previous 4 weeks and 12 months in the severely versus nonpolluted community were estimated in logistic regression analysis controlling for age and gender. The risk of nasal symptoms (4 weeks OR 1.40, 95% CI 0.59-3.31; 12 months OR 2.47, 95% CI 0.93-6.53), cough (4 weeks OR 1.83, 95% CI 0.75-4.45; 12 months OR 2.28, 95% CI 0.95-5.47), eye symptoms (12 months OR 1.15, 95% CI 0.43-3.05), and headache (12 months OR 1.77, 95% CI 0.69-4.54) was considerably increased in the severely polluted community, although not quite reaching statistical significance. The results suggest that exposure to malodorous sulfur compounds may affect the health of children.
我们评估了长期暴露于纸浆厂排放的环境空气中恶臭含硫化合物对儿童眼睛、呼吸道症状及头痛的影响。此前尚未有关于儿童环境暴露于这些化合物产生不良健康影响的报道。134名居住在重度污染社区（n = 42）、中度污染社区（n = 62）和农村无污染社区（n = 30）的儿童的家长对一份横断面调查问卷做出了回应。回应率为83%。在控制年龄和性别的逻辑回归分析中，估计了重度污染社区与无污染社区在前4周和12个月内出现症状的调整优势比（OR）。在重度污染社区，出现鼻部症状（4周OR 1.40，95% CI 0.59 - 3.31；12个月OR 2.47，95% CI 0.93 - 6.53）、咳嗽（4周OR 1.83，95% CI 0.75 - 4.45；12个月OR 2.28，95% CI 0.95 - 5.47）、眼部症状（12个月OR 1.15，95% CI 0.43 - 3.05）和头痛（12个月OR 1.77，95% CI 0.69 - 4.54）的风险显著增加，尽管未完全达到统计学显著性。结果表明，暴露于恶臭含硫化合物可能会影响儿童健康。
