Ho C M, Khuzaiah R, Yasmin A M
Department of Paediatrics, Hospital Besar, Kuala Lumpur.
Med J Malaysia. 1994 Mar;49(1):29-35.
Primary varicella-zoster virus infection in children with haematological malignancy is a life threatening disease. In one year, there were 10 cases of varicella and 2 cases of zoster among these children as well as 5 mothers who were accompanying their children who developed varicella in the oncology ward. Two children died of fulminating disease despite aggressive antiviral and supportive treatment. Acyclovir can be used in treatment and prophylaxis in exposed susceptible children. Varicella -zoster immune globulin is not available in this country. Vaccination with live virus has been shown to be protective in immunocompromised children and needs consideration.
血液系统恶性肿瘤患儿的原发性水痘-带状疱疹病毒感染是一种危及生命的疾病。在一年时间里，这些患儿中有10例患水痘，2例患带状疱疹，还有5名陪伴孩子在肿瘤病房的母亲也感染了水痘。尽管进行了积极的抗病毒和支持治疗，仍有两名儿童死于暴发性疾病。阿昔洛韦可用于暴露的易感儿童的治疗和预防。该国没有水痘-带状疱疹免疫球蛋白。已证明活病毒疫苗对免疫功能低下的儿童有保护作用，值得考虑。
