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[高血压急症。1. 发病机制与症状学]

[Hypertensive crises. 1. Pathogenesis and symptomatology].

作者信息

Fog L, Pedersen O L

机构信息

Medicinsk afdeling, Viborg Sygehus.

出版信息

Ugeskr Laeger. 1995 Dec 18;157(51):7135-9.

PMID:8545928
Abstract

Hypertensive crisis is a medical emergency presenting with a severely increased blood pressure. The condition is associated with a state of increased vasoconstriction, coexisting hyponatriaemia and hypovolaemia. Besides the absolute level of blood pressure evidence of organ damage is also important in initial judgement of the case. Hypertensive crises are most commonly seen in younger patients with essential hypertension and in patients with secondary hypertension. It is unknown why a patient with hypertension suddenly develops a hypertensive crisis, but the renin-angiotension system seems to play an important role. Untreated, the disease will lead to irreversible end-organ damage. Hypertensive crises may be divided into "hypertensive emergencies" with evidence of severe new and/or progressive end-organ damage, requiring careful reduction of blood pressure within an hour, and "hypertensive urgencies" with no evidence of end-organ damage or complications where reduction of blood pressure to a safe level must be achieved within a few hours.

摘要

高血压危象是一种伴有血压严重升高的医疗急症。该病症与血管收缩增强、并存低钠血症和血容量不足的状态相关。除了血压的绝对水平外,器官损害的证据在病例的初步判断中也很重要。高血压危象最常见于原发性高血压的年轻患者和继发性高血压患者。尚不清楚高血压患者为何会突然发生高血压危象,但肾素 - 血管紧张素系统似乎起着重要作用。若不治疗,该疾病将导致不可逆的终末器官损害。高血压危象可分为“高血压急症”,即有严重的新的和/或进行性终末器官损害的证据,需要在一小时内谨慎降低血压;以及“高血压亚急症”,即没有终末器官损害或并发症的证据,必须在几小时内将血压降至安全水平。

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