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[支气管哮喘患者血小板单采术的远期结果]

[The late results of thrombocytapheresis in bronchial asthma patients].

作者信息

Tatarskiĭ A R, Emirova A S, Bobkov E V, Alieva K M, Karnaushkina M A

出版信息

Ter Arkh. 1993;65(3):19-22.

PMID:8059374
Abstract

A long-term follow-up (within 18 months) has been conducted of bronchial asthma (BA) patients (a total of 29 cases with atopic, aspirin and mixed BA forms) subjected to thrombocytapheresis. The examination performed in 1-2 month intervals included a berotec test, assessment of platelet aggregation, platelet intracellular calcium metabolism, external respiration function (ERF). The treatment resulted in remission of 4-18 month duration. It was characterized by ERF normalization, high sensitivity to sympathomimetics, platelet status improvement. The best results were achieved in the groups of atopic and aspirin asthma patients. The findings allow recommendation of thrombocytapheresis as a method of choice in combined therapy of BA.

摘要

对接受血小板单采术的支气管哮喘(BA)患者(共29例,包括特应性、阿司匹林性和混合型BA)进行了为期18个月的长期随访。每隔1 - 2个月进行的检查包括贝罗特克试验、血小板聚集评估、血小板细胞内钙代谢、肺通气功能(ERF)。治疗使病情缓解持续4 - 18个月。其特征为ERF恢复正常、对拟交感神经药高度敏感、血小板状态改善。特应性哮喘患者组和阿司匹林性哮喘患者组取得了最佳效果。这些研究结果表明,血小板单采术可作为BA联合治疗的首选方法。

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