Amosov G G, Tolpekin V E
Anesteziol Reanimatol. 1994 Mar-Apr(2):15-7.
Hemodynamics was studied experimentally in 36 mongrel dogs during ventricular fibrillation (VF) in conditions of controlled lung ventilation with tidal volumes (TV) 7, 14 and 21 ml/kg and minute ventilation (MV) 140 ml/(min.kg). Cardiac output determined in ascending aorta varied from 4.1 to 7.3 ml/(min.kg) depending on TV and evaluation period with initial values prior to VF 101-110 ml/(min.kg). In 12 experiments using TV of 14 ml/kg acid-base balance and blood gas composition in central and peripheral circulation compartments have been determined. High HbO2 and pO2 levels in peripheral vessels have been noted; HbO2 difference between aortic blood and caudal vein blood was 37% on minute 30 and 28% between aortic and peripheral venous (femoral vein) blood.
在36只杂种犬心室颤动(VF)期间,在潮气量(TV)为7、14和21ml/kg以及分钟通气量(MV)为140ml/(min·kg)的控制肺通气条件下对血流动力学进行了实验研究。升主动脉中测定的心输出量根据潮气量和评估期的不同,在4.1至7.3ml/(min·kg)之间变化,心室颤动前的初始值为101-110ml/(min·kg)。在12个使用14ml/kg潮气量的实验中,测定了中央和外周循环隔室中的酸碱平衡和血气成分。外周血管中观察到高血红蛋白氧(HbO2)和氧分压(pO2)水平;在第30分钟时,主动脉血与尾静脉血之间的HbO2差异为37%,主动脉血与外周静脉(股静脉)血之间的差异为28%。