14-表二氢卷柏醌B和14-表卷柏醌B，来自子囊菌新保加利亚纯发酵的抗生素：结构解析及其对血小板聚集的影响
14-epidihydrocochlioquinone B and 14-epicochlioquinone B, antibiotics from fermentations of the ascomycete Neobulgaria pura: structure elucidation and effects on platelet aggregation.
作者信息
Lorenzen K, Anke T, Anders U, Hindermayr H, Hansske F
机构信息
LB Biotechnologie der Universität, Kaiserslautern, Bundesrepublik Deutschland.
出版信息
Z Naturforsch C J Biosci. 1994 May-Jun;49(5-6):312-20. doi: 10.1515/znc-1994-5-606.
14-Epicochlioquinone B (1) and 14-epidihydrocochlioquinone B (2) were isolated from submerged cultures of Neobulgaria pura (Pers. ex Fr.) Petrak. 14-Epicochlioquinone B is a potent inhibitor of human and bovine platelet aggregation stimulated by different inducers. 14-Epidihydrocochlioquinone B does not inhibit the aggregation of platelets. In addition, both 1 and 2 exhibited cytotoxic and antimicrobial activities.
从纯新球盖菇（Pers. ex Fr.）Petrak的深层培养物中分离出了14-表球盖醌B（1）和14-表二氢球盖醌B（2）。14-表球盖醌B是不同诱导剂刺激人及牛血小板聚集的有效抑制剂。14-表二氢球盖醌B不抑制血小板聚集。此外，化合物1和2均表现出细胞毒性和抗菌活性。
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