Tomatis L
International Agency for Research on Cancer, Lyon, France.
Cancer Lett. 1994 Aug 15;83(1-2):139-42. doi: 10.1016/0304-3835(94)90310-7.
The most reasonable and socially acceptable development of cancer prevention should be the blending of the population approach, that is the shifting of the distribution of risk factors across an entire population in a favourable direction, with the high risk approach aimed at the identification, surveillance and possibly early interventions on individuals with particularly high values of predisposition to cancer. Interventions aimed at reducing or eliminating genetically determined weaknesses with regard to interactions with the environment, will not make, therefore, in any way obsolete or redundant, interventions aimed at eliminating or reducing exposure to environmental carcinogens.
癌症预防最合理且社会可接受的发展方向应是将人群方法(即将风险因素在整个人口中的分布朝着有利方向转变)与高危方法相结合,后者旨在识别、监测并可能对具有特别高癌症易感性的个体进行早期干预。因此,旨在减少或消除与环境相互作用方面由基因决定的弱点的干预措施,绝不会使旨在消除或减少接触环境致癌物的干预措施过时或多余。