Gray S F, Gunnell D J, Peters T J
Research and Development Directorate, South Western Regional Health Authority, Bristol.
Epidemiol Infect. 1994 Aug;113(1):95-102. doi: 10.1017/s0950268800051505.
Giardia lamblia is a common and increasing cause of gastrointestinal illness in the UK. We report a case-control study that examined risk factors for giardiasis. Patients with giardiasis were identified from reports to the Consultants in Communicable Disease in Avon and Somerset, and age-sex matched controls were obtained from their general practitioners' lists. Details of travel history, water consumption and recreational water use were collected by postal questionnaire. Over the period July 1992 to May 1993, 74 cases and 108 matched controls were obtained. The data were analysed using conditional logistic regression. Swimming appeared to be an independent risk factor for giardiasis (odds ratio 2.4, 95% CI 1.0 to 6.1, P = 0.050). Travel (P = 0.001), particularly to developing countries, and type of travel (P = 0.004)--that is, camping, caravanning or staying in holiday chalets--were also observed to be significant risk factors. Other recreational water use and drinking potentially contaminated water were found to be not statistically significant after adjustment for other factors.
蓝氏贾第鞭毛虫是英国胃肠道疾病常见且日益增多的病因。我们报告了一项病例对照研究,该研究调查了贾第虫病的危险因素。通过向埃文和萨默塞特传染病顾问的报告确定了贾第虫病患者,并从他们的全科医生名单中获取了年龄和性别匹配的对照。通过邮寄问卷收集旅行史、水消费量和娱乐用水使用情况的详细信息。在1992年7月至1993年5月期间,获得了74例病例和108例匹配对照。使用条件逻辑回归分析数据。游泳似乎是贾第虫病的一个独立危险因素(比值比2.4,95%可信区间1.0至6.1,P = 0.050)。旅行(P = 0.001),特别是前往发展中国家的旅行,以及旅行类型(P = 0.004)——即露营、乘坐大篷车旅行或住在度假木屋——也被观察到是显著的危险因素。在对其他因素进行调整后,发现其他娱乐用水使用和饮用可能受污染的水在统计学上不显著。