Hoffmann R, Lohner M, Böhm N, Schaefer H E, Leititis J
Institute of Pathology, Albert-Ludwigs-University, Freiburg, FRG.
Pathol Res Pract. 1994 Jan;190(1):77-81; discussion 81-3. doi: 10.1016/S0344-0338(11)80499-1.
Staphylococcal scaled-skin syndrome (SSSS) is a toxin-related epidermolytic disease that usually affects infants and children under 5 years. We report herein a case of a premature infant who had developed SSSS after an infection of the pharynx with staphylococci and who died of septicaemia due to pseudomonas aeruginosa. The primary mechanism of action of epidermolysin still remains unknown. We demonstrate that acantholysis is due to an early edema of the intercellular space with separation of ultrastructurally unaltered desmosomes.
葡萄球菌性烫伤样皮肤综合征（SSSS）是一种与毒素相关的表皮松解性疾病，通常影响5岁以下的婴儿和儿童。我们在此报告一例早产儿，其在咽部被葡萄球菌感染后发生了SSSS，并因铜绿假单胞菌败血症死亡。表皮松解毒素的主要作用机制仍然未知。我们证明棘层松解是由于细胞间空间早期水肿以及超微结构未改变的桥粒分离所致。
