Achermann P, Borbély A A
Institute of Pharmacology, University of Zürich, Switzerland.
Biol Cybern. 1994;71(2):115-21. doi: 10.1007/BF00197314.
The two-process model of sleep regulation postulates that a homeostatic and a circadian process underlie sleep regulation. The timing of sleep and waking is accounted for by the interaction of these two processes. The assumptions of two separate processes or of a single process resulting from their additive interaction are mathematically equivalent but conceptually different. Based on an additive interaction, subjective alertness ratings in a forced desynchrony protocol and subjective sleepiness ratings in a photoperiod experiment were simulated. The correspondence between empirical and simulated data supports the basic assumption of the model.
睡眠调节的双过程模型假定，睡眠调节基于一个稳态过程和一个昼夜节律过程。睡眠和清醒的时间由这两个过程的相互作用决定。两个独立过程或它们相加相互作用产生的单一过程的假设在数学上是等效的，但在概念上有所不同。基于相加相互作用，模拟了强制失同步方案中的主观警觉性评分和光周期实验中的主观嗜睡评分。实验数据与模拟数据之间的对应关系支持了该模型的基本假设。
