Probst L E, Wilkinson J, Nichols B D
Department of Ophthalmology, University Hospital, University of Western Ontario, London.
Can J Ophthalmol. 1994 Apr;29(2):77-80.
In the antibiotic era the ophthalmologist has become less familiar with the diagnosis of congenital syphilis. The recognition of this disease is crucial, as neurosyphilis or cardiovascular syphilis will develop in a substantial number of patients with latent congenital syphilis without the appropriate treatment. We describe eight patients aged 60 years or more who presented with refractive problems in whom congenital syphilis was subsequently diagnosed for the first time. One patient was found to have neurosyphilis and the highest VDRL result ever recorded by the London Public Health Laboratory. Seven patients required extensive antibiotic therapy, and three subsequently underwent successful ocular surgery. These cases illustrate the importance of recognizing this treatable disease.
在抗生素时代，眼科医生对先天性梅毒的诊断已变得不太熟悉。认识这种疾病至关重要，因为在大量未经适当治疗的潜伏性先天性梅毒患者中会发展为神经梅毒或心血管梅毒。我们描述了8例60岁及以上出现屈光问题的患者，他们随后首次被诊断出患有先天性梅毒。其中1例患者被发现患有神经梅毒，其VDRL结果是伦敦公共卫生实验室有记录以来最高的。7例患者需要进行广泛的抗生素治疗，3例随后成功接受了眼科手术。这些病例说明了认识这种可治疗疾病的重要性。
