Padberg B C, Holzhausen H J, Weinland G, August C, Schröder S
Departement Pathologie, Universität Zürich.
Pathologe. 1994 Jun;15(3):176-80. doi: 10.1007/s002920050042.
An example of a benign haemorrhagic spindle cell tumour of the lymph node (synonym: intranodal myofibroblastoma) is presented, which was first described 5 years ago and has not as yet been documented in the German literature. This rare benign mesenchymal neoplasm of the lymph node occurs almost exclusively in the inguinal region. Diagnostic criteria include its composition of myofibroblastic cells (with immunoreactivity for vimentin and actin), which may show nuclear palisading, the presence of peripheral haemorrhage zones and the occurrence of characteristic amianthoid structures, which have the ultrastructural appearance of dense meshworks of collagen fibers. Knowledge of this tumour entity is important for differential diagnosis of primary and secondary malignant mesenchymal neoplasias of the lymph node.
本文介绍了一例淋巴结良性出血性梭形细胞瘤(同义词:结内肌成纤维细胞瘤),该肿瘤于5年前首次被描述,德国文献中尚未有相关记载。这种罕见的淋巴结良性间叶性肿瘤几乎仅发生于腹股沟区。诊断标准包括其由肌成纤维细胞组成(波形蛋白和肌动蛋白免疫反应阳性),可出现核栅栏状排列、外周出血区以及特征性石棉样结构,后者在超微结构上表现为胶原纤维的致密网络。了解这种肿瘤实体对于淋巴结原发性和继发性恶性间叶性肿瘤的鉴别诊断很重要。