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[血液透析患者和肾移植患者中的抗丙型肝炎病毒抗体]

[Anti-HCV antibodies among hemodialysed and kidney-transplanted patients].

作者信息

Juszczyk J, Flieger J, Syczewska M, Krzymański M

机构信息

Klinika Chorób Zakaźnych AM, Poznaniu.

出版信息

Przegl Epidemiol. 1994;48(1-2):3-9.

PMID:8073139
Abstract

We have studied from two hemodialysed centers to determine the prevalence of hepatitis C virus infection in hemodialysis 142 patients and 147 renal-transplant patients. Serum samples were tested for antibody by "Ortho HCV 2.0 ELISA test System" second generation assay. Antibody to hepatitis C virus was detected in 81 (57.04%) and 85 (57.82%) patients respectively. Age-related differences were not clear, but significantly were noted in hemodialysis patients. Patients with a history blood transfusion in both groups tended to have significantly high anti-HCV positivity rate. There was a tendency for a longer duration of hemodialysis to coincide with higher positivity anti-HCV.

摘要

我们对两个血液透析中心进行了研究,以确定142例血液透析患者和147例肾移植患者中丙型肝炎病毒感染的患病率。血清样本通过“Ortho HCV 2.0 ELISA检测系统”第二代检测法检测抗体。分别在81例(57.04%)和85例(57.82%)患者中检测到丙型肝炎病毒抗体。年龄相关差异不明显,但在血液透析患者中差异显著。两组中有输血史的患者抗-HCV阳性率往往显著较高。血液透析时间较长往往与抗-HCV阳性率较高相关。

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