Gaultier C, Reinberg A, Girard F, Gerbeaux J
C R Acad Hebd Seances Acad Sci D. 1975 Mar 10;280(10):1253-5.
Circadian rhythms in lung resistance (R1) and dynamic compliance (C1dyn) of 7 healthy children (6 to 10 years) were validated (p less than .05) and then quantified (cosinor method); subjects' synchronization: light on at 0700; light off at 2100. Measurements were performed at fixed per hours (0730, 1130, 1630 and 2230) before and after the inhalation of a beta sympathomimetic bronchodilatator: minus 2mg orciprenaline. The measurements carried out after orciprenaline inhalation show a flattening of the curves, both circadian rhythms in R1 and C1 dyn are not detected (p greater than .05).
对7名健康儿童（6至10岁）的肺阻力（R1）和动态顺应性（C1dyn）的昼夜节律进行了验证（p小于0.05），然后进行了量化（余弦分析法）；受试者的同步情况：07:00开灯；21:00关灯。在吸入β-拟交感神经支气管扩张剂（-2mg奥西那林）前后，于固定的每小时（07:30、11:30、16:30和22:30）进行测量。吸入奥西那林后进行的测量显示曲线变平，R1和C1dyn的昼夜节律均未检测到（p大于0.05）。
