[离体兔关节软骨细胞对人血清生长调节素活性的敏感性]

[Sensitivity of isolated rabbit articular chrondrocytes to the somatomedin activity of human serum].

作者信息

Binet E, Schlumberger A, Fournier F, Chaussain J L, Job J C

出版信息

C R Acad Hebd Seances Acad Sci D. 1975 Apr 14;280(14):1713-6.

Abstract

Rabbit articular chondrocytes, isolated and incubated in vitro, incorporate tritium-labelled thymidine. Thymidine incorporation is stimulated by normal human serum, this effect being related to serum concentration and increased by addition of poly-DL-ornithine. The stimulatory effect of the serum from hypopituitary dwarfs is low and is not increased by poly-DL-ornithine.

摘要

体外分离并培养的兔关节软骨细胞会摄取氚标记的胸腺嘧啶核苷。正常人血清可刺激胸腺嘧啶核苷的摄取，这种效应与血清浓度相关，且添加聚-DL-鸟氨酸后会增强。垂体功能减退性侏儒症患者血清的刺激作用较弱，添加聚-DL-鸟氨酸后也不会增强。