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[离体兔关节软骨细胞对人血清生长调节素活性的敏感性]

[Sensitivity of isolated rabbit articular chrondrocytes to the somatomedin activity of human serum].

作者信息

Binet E, Schlumberger A, Fournier F, Chaussain J L, Job J C

出版信息

C R Acad Hebd Seances Acad Sci D. 1975 Apr 14;280(14):1713-6.

PMID:807364
Abstract

Rabbit articular chondrocytes, isolated and incubated in vitro, incorporate tritium-labelled thymidine. Thymidine incorporation is stimulated by normal human serum, this effect being related to serum concentration and increased by addition of poly-DL-ornithine. The stimulatory effect of the serum from hypopituitary dwarfs is low and is not increased by poly-DL-ornithine.

摘要

体外分离并培养的兔关节软骨细胞会摄取氚标记的胸腺嘧啶核苷。正常人血清可刺激胸腺嘧啶核苷的摄取，这种效应与血清浓度相关，且添加聚-DL-鸟氨酸后会增强。垂体功能减退性侏儒症患者血清的刺激作用较弱，添加聚-DL-鸟氨酸后也不会增强。

相似文献

1
[Sensitivity of isolated rabbit articular chrondrocytes to the somatomedin activity of human serum].[离体兔关节软骨细胞对人血清生长调节素活性的敏感性]
C R Acad Hebd Seances Acad Sci D. 1975 Apr 14;280(14):1713-6.
2
Response of isoalted rabbit articular and epiphyseal chondrocytes to rat liver somatomedin.离体兔关节软骨细胞和骨骺软骨细胞对大鼠肝脏生长介素的反应。
J Endocrinol. 1975 Jul;66(1):71-8. doi: 10.1677/joe.0.0660071.
3
Determination of human serum somatomedin activity in rabbit articular chondrocytes isolated and incubated in vitro-a critical study.体外分离并培养的兔关节软骨细胞中人血清生长调节素活性的测定——一项关键研究
Biomedicine. 1979 Feb;30(1):31-40.
4
Effect of somatomedin-C/insulin-like growth factor I and growth hormone on cultured growth plate and articular chondrocytes.生长调节素-C/胰岛素样生长因子I和生长激素对培养的生长板及关节软骨细胞的作用。
Pediatr Res. 1989 Jan;25(1):76-82. doi: 10.1203/00006450-198901000-00017.
5
An assay for plasma somatomedin: [3H]thymidine incorporation by isolated rabbit chondrocytes.血浆生长调节素的一种测定方法：分离的兔软骨细胞对[3H]胸腺嘧啶核苷的摄取。
J Endocrinol. 1977 Aug;74(2):205-12. doi: 10.1677/joe.0.0740205.
6
Effect of partially purified human somatomedin on human fetal and postnatal cartilage in vitro.部分纯化的人生长调节素对人胎儿及出生后软骨的体外作用
Early Hum Dev. 1983 Jul;8(2):135-40. doi: 10.1016/0378-3782(83)90069-5.
7
Stimulation of DNA synthesis in isolated chondrocytes by somatomedin. II. Validation of the assay for clinical use and comparison with stimulation of protein synthesis.生长调节素对分离软骨细胞DNA合成的刺激作用。II. 该检测方法临床应用的验证及与蛋白质合成刺激作用的比较
J Clin Endocrinol Metab. 1976 Oct;43(4):847-51. doi: 10.1210/jcem-43-4-847.
8
Actions of growth hormone, prolactin and thyroxine on serum somatomedin-like activity and growth in hypopituitary dwarf mice.
J Endocrinol. 1977 Aug;74(2):223-9. doi: 10.1677/joe.0.0740223.
9
Stimulation of cartilage zones of the calf costochondral growth plate in vitro by growth hormone dependent rat plasma somatomedin activity.生长激素依赖性大鼠血浆生长调节素活性对体外培养的小牛肋软骨生长板软骨区的刺激作用。
J Endocrinol. 1979 Nov;83(2):219-27. doi: 10.1677/joe.0.0830219.
10
Change in response with age of human articular cartilage to plasma somatomedin activity.人类关节软骨对血浆生长调节素活性的反应随年龄的变化
Calcif Tissue Int. 1979 Nov 26;29(2):89-94. doi: 10.1007/BF02408062.

引用本文的文献

1
Somatomedin activity in synovial fluid from patients with joint diseases.关节疾病患者滑液中的生长调节素活性。
Ann Rheum Dis. 1978 Aug;37(4):303-14. doi: 10.1136/ard.37.4.303.