Rousselet M C, Guyetant S, Croue A, Limal J M, Saint-André J P
Laboratoire d'Anatomie Pathologique, CHU, Angers.
Arch Anat Cytol Pathol. 1994;42(1):10-5.
A 11-year-old girl presented in 1990 with bilateral goiter, hypothyroidism and thyroid auto-antibodies and was treated for Hashimoto's thyroiditis. In 1991, a cervical lymph node metastasis revealed diffuse sclerosing papillary carcinoma (DSPC) of the right thyroid lobe and chronic lymphocytic thyroiditis of the left lobe. The patient is in remission in 1993 (total follow-up, 39 months). The review of 60 previously reported cases of DSPC shows a predilection for young people, a high incidence of lymph node and pulmonary metastases; however the mortality rate is quite low, reflecting either the good prognosis linked to a young age in papillary thyroid carcinomas, or the short duration of the follow-up preventing assessment of the behaviour of DSPC.
一名11岁女孩于1990年因双侧甲状腺肿、甲状腺功能减退和甲状腺自身抗体就诊，被诊断为桥本甲状腺炎并接受治疗。1991年，颈部淋巴结转移显示右甲状腺叶为弥漫性硬化性乳头状癌（DSPC），左叶为慢性淋巴细胞性甲状腺炎。该患者于1993年病情缓解（总随访时间39个月）。对先前报道的60例DSPC病例的回顾显示，此病好发于年轻人，淋巴结和肺转移发生率高；然而死亡率相当低，这要么反映了甲状腺乳头状癌与年轻相关的良好预后，要么反映了随访时间短，无法评估DSPC的病情进展。
