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[健康受试者和支气管哮喘患者中β-肾上腺素能淋巴细胞受体的密度]

[Density of beta-adrenergic lymphocyte receptors in health subjects and patients with bronchial asthma].

作者信息

Passowicz-Muszyńska E, Małolepszy J, Jankowska R

机构信息

Katedry i Kliniki Chorób Wewnetrznych i Alergologii AM we Wrocławiu.

出版信息

Pneumonol Alergol Pol. 1994;62(1-2):12-7.

PMID:8075605
Abstract

In this study were involved 45 subjects: 15 healthy (group I), 15 patients with atopic mild bronchial asthma (group II) and 15 asthmatics with moderate bronchial asthma. Peripheral blood lymphocyte beta-2-adrenergic receptor (BAR) density and affinity were determined. Radiolabelled ligandbinding assays determine receptor density and affinity were performed. Significant differences in lymphocyte BAR density were found when healthy subjects and moderate bronchial asthma patients were compared.

摘要

本研究纳入了45名受试者:15名健康者(第一组)、15名患有特应性轻度支气管哮喘的患者(第二组)和15名中度支气管哮喘患者。测定了外周血淋巴细胞β-2-肾上腺素能受体(BAR)的密度和亲和力。采用放射性标记配体结合试验测定受体密度和亲和力。比较健康受试者和中度支气管哮喘患者时,发现淋巴细胞BAR密度存在显著差异。

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