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Cloning and sequence of the Xenopus laevis homologue of the midkine cDNA.

作者信息

Fu C, Maminta-Smith L D, Guo C, Deuel T F

机构信息

Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110.

出版信息

Gene. 1994 Sep 2;146(2):311-2. doi: 10.1016/0378-1119(94)90312-3.

Abstract

The Xenopus laevis (Xl) homologue of the midkine-encoding gene (MK) has been isolated and sequenced from a X. laevis cDNA library made from the head region of stage-22 embryo. The nucleotide and deduced amino-acid sequences show a high degree of conservation with the avian and mammalian MK and pleiotrophin (PTN) genes and gene products. Highly conserved domains may indicate important regions for the function of the MK and PTN proteins.

摘要

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