Fu C, Maminta-Smith L D, Guo C, Deuel T F
Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110.
Gene. 1994 Sep 2;146(2):311-2. doi: 10.1016/0378-1119(94)90312-3.
The Xenopus laevis (Xl) homologue of the midkine-encoding gene (MK) has been isolated and sequenced from a X. laevis cDNA library made from the head region of stage-22 embryo. The nucleotide and deduced amino-acid sequences show a high degree of conservation with the avian and mammalian MK and pleiotrophin (PTN) genes and gene products. Highly conserved domains may indicate important regions for the function of the MK and PTN proteins.