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脊神经在神经纤维瘤病中的受累情况。

Involvement of spinal nerves in neurofibromatosis.

作者信息

Tatagiba M, Bini W, Sepehrnia A, Eichhorn R, Kleider A, Samii M

机构信息

Neurosurgical Clinic, Nordstadt Hospital, Hannover, Fed. Rep. of Germany.

出版信息

Neurosurg Rev. 1994;17(1):43-9. doi: 10.1007/BF00309986.

DOI:10.1007/BF00309986
PMID:8078608
Abstract

Spinal tumors are a frequent form of manifestation of neurofibromatosis. Out of 171 patients, who have been operated on over a ten years period on spinal tumors, 7 patients had neurofibromatosis (4.1%). A total of 9 operations were performed, removing 20 spinal tumors. Three patients had multiple neurofibromas. Half of the neurofibromas had a dumbbell configuration with a larger extraspinal extension. In three patients a family history of neurofibromatosis and typical dermatological signs were evident. Two cases will be selected and the basic concept regarding treatment and the risks involved will be discussed.

摘要

脊柱肿瘤是神经纤维瘤病常见的一种表现形式。在171例接受了长达十年脊柱肿瘤手术的患者中,7例患有神经纤维瘤病(4.1%)。总共进行了9次手术,切除了20个脊柱肿瘤。3例患者患有多发性神经纤维瘤。半数神经纤维瘤呈哑铃状,椎管外延伸部分较大。3例患者有神经纤维瘤病家族史且有典型的皮肤病体征。将选取2个病例,并讨论其治疗的基本理念及相关风险。

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Central neurofibromatosis with bilateral acoustic neuroma: genetic, clinical and biochemical distinctions from peripheral neurofibromatosis.伴有双侧听神经瘤的中枢性神经纤维瘤病:与周围性神经纤维瘤病在遗传、临床及生化方面的差异
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Loss of genes on chromosome 22 in tumorigenesis of human acoustic neuroma.22号染色体上的基因缺失在人类听神经瘤肿瘤发生中的作用
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Spinal neurofibromas: a report of 66 cases and a comparison with meningiomas.脊髓神经纤维瘤:66例报告及与脑膜瘤的比较
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