Høieggen A, Enger E
Medisinsk klinikk, Ullevål sykehus, Oslo.
Tidsskr Nor Laegeforen. 1994 Apr 30;114(11):1299-300.
Three well trained young persons developed rhabdomyolysis after heavy physical exercise. Two of them developed acute renal failure and underwent peritoneal dialysis for a prolonged period. It is poorly understood why some people develop rhabdomyolysis under such conditions. Various explanations are discussed. It is also not completely understood why some, but by no means all, patients with creatine phosphokinase (CK) elevation develop acute renal failure. The nephrotoxicity of myoglobin is decreased by forced alkaline diuresis. Rhabdomyolysis may cause few or no symptoms, but can threaten life. It is important that physicians are aware of the condition, and know that it may develop after physical exercise alone.
三名训练有素的年轻人在剧烈体育锻炼后发生了横纹肌溶解症。其中两人发展为急性肾衰竭，并接受了长时间的腹膜透析。目前尚不清楚为什么有些人在这种情况下会发生横纹肌溶解症。文中讨论了各种解释。同样也不完全清楚为什么一些（但绝非所有）肌酸磷酸激酶（CK）升高的患者会发展为急性肾衰竭。通过强制碱性利尿可降低肌红蛋白的肾毒性。横纹肌溶解症可能几乎不引起症状或完全没有症状，但却可能危及生命。医生了解这种情况很重要，并且要知道它可能仅在体育锻炼后就会发生。
