Derisquebourg T, Dubois P, Devogelaer J P, Meys E, Duquesnoy B, Nagant de Deuxchaisnes C, Delcambre B, Marchandise X
Centre A. Verhaeghe, Hôpital B, CHU de Lille, France.
Calcif Tissue Int. 1994 Jun;54(6):461-5. doi: 10.1007/BF00334323.
The value of a new computerized radiogrammetric method of assessment of the second metacarpal has been evaluated, and its results have been compared with those of single (SPA) and dual photon absorptiometry measurements (forearm and spine) in 74 and 79 postmenopausal women, respectively. Standard hand X-rays were digitized by a video-camera connected to a microcomputer. The combined cortical thickness (CCT) was automatically calculated in a zone of 10 mm around the midpart of the second metacarpal. The intra- and interobserver coefficients of variation were close to 1%. The correlation between CCT and SPA of the proximal and midforearm (with a significant amount of cortical bone) was satisfactory (r = 0.62 and 0.50, respectively; P < 0.001). The correlation between CCT and osteodensitometry of sites comprising more trabecular bone were not so good (0.50 for lumbar and 0.44 for distal forearm bone mineral density, respectively), but still significant (P < 0.001). Radiogrammetry proved unaffected by a change of X-ray apparatus, as measurements of 48 metacarpals radiographed by two different kinds of X-ray apparatus were not significantly different. Radiogrammetry is by no means the best method to evaluate bone mass. Its automation did not improve the correlation with osteodensitometric values. Radiogrammetry is still of interest in mass screening, particularly when other more expensive techniques such as osteodensitometric methods of bone mass measurement are not readily available. Its automation makes it simpler, faster, and more precise, rendering its use easier on a larger scale.
一种评估第二掌骨的新型计算机放射测量方法的价值已得到评估，并将其结果分别与74名和79名绝经后女性的单光子吸收测量法（SPA）和双能光子吸收测量法（测量前臂和脊柱）的结果进行了比较。标准手部X线片通过连接到微型计算机的摄像机进行数字化处理。在第二掌骨中部周围10毫米的区域自动计算皮质骨总厚度（CCT）。观察者内和观察者间变异系数接近1%。CCT与近端和前臂中部（含有大量皮质骨）的SPA之间的相关性良好（分别为r = 0.62和0.50；P < 0.001）。CCT与包含更多小梁骨部位的骨密度测量之间的相关性没那么好（腰椎为0.50，远端前臂骨密度为0.44），但仍具有显著性（P < 0.001）。由于用两种不同类型X线设备拍摄的48根掌骨的测量结果无显著差异，放射测量法被证明不受X线设备变化的影响。放射测量法绝不是评估骨量的最佳方法。其自动化并未改善与骨密度测量值的相关性。放射测量法在大规模筛查中仍具有重要意义，尤其是当其他更昂贵的技术（如骨量测量的骨密度测量方法）不易获得时。其自动化使其更简单、更快、更精确，使其在更大规模上的使用更容易。
