Bouloy M, Colbère F, Krams-Ozden S, Vialat P, Garapin A C, Hannoun C, Lépine P
C R Acad Hebd Seances Acad Sci D. 1975 Jan 13;280(2):213-5.
RNA dependent RNA polymerase has been demonstrated in purified Lumbo virus (Bunyavirus) which contains a single stranded segmented RNA. Divalent cations (Mn++ and Mg++) are required for optimal in vitro activity. Reaction products can be specifically annealed with the viral genome.
已在含有单链分段RNA的纯化隆波病毒(布尼亚病毒)中证实了RNA依赖性RNA聚合酶。二价阳离子(Mn++和Mg++)对于最佳体外活性是必需的。反应产物可与病毒基因组特异性退火。