Courgeon A M
C R Acad Hebd Seances Acad Sci D. 1975 Jun 9;280(22):2563-6.
The action of juvenile hormone used alone or combined with ecdysterone was studied on in vitro diploid cell lines or clones of Drosophila. The solubility of juvenile hormone in the culture medium was estimated to be 10(-8) M. At this concentration, which can be considered as physiological, juvenile hormone slows down the process of ecdysone-induced morphological modifications of the cells. This action is reversible. Concentrations of about 10(-4) M inhibit all reactions to ecdysterone and bring about the death of the cells. This effect is probably non-specific.
单独使用或与蜕皮激素联合使用的保幼激素对果蝇的体外二倍体细胞系或克隆的作用进行了研究。保幼激素在培养基中的溶解度估计为10^(-8) M。在这个可被视为生理浓度的情况下,保幼激素会减缓蜕皮激素诱导的细胞形态改变过程。这种作用是可逆的。约10^(-4) M的浓度会抑制对蜕皮激素的所有反应并导致细胞死亡。这种效应可能是非特异性的。