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关于皮特斯拉范围磁场对帕金森病独特疗效的进一步观察。

Further observations on the unique efficacy of picoTesla range magnetic fields in Parkinson's disease.

作者信息

Sandyk R, Derpapas K

机构信息

NeuroCommunication Research Laboratories, Danbury, CT 06811.

出版信息

Int J Neurosci. 1993 Mar-Apr;69(1-4):167-83. doi: 10.3109/00207459309003328.

DOI:10.3109/00207459309003328
PMID:8083004
Abstract

External application of picoTesla range magnetic fields (MF) has been reported recently to be efficacious in the treatment of patients with Parkinson's disease (PD) including those who manifest levodopa-related dyskinesias. In the present communication, we present four additional Parkinsonian patients who showed, within a brief period of time, marked improvement in motor symptoms after therapy with MF. Three of the patients had been maintained on antiParkinsonian medication during treatment with MF while the fourth patient had never received pharmacotherapy. Improvement with magnetic therapy was noted not only in the motor sphere (resting tremor, gait apraxia, postural instability), but also in nonmotor aspects of the disease including mood, sleep, pain, anorexia, autonomic, and cognitive functions attesting to the unique efficacy of external picoTesla range MF in the treatment of Parkinsonism. Poverty of facial expression (hypomimia, "masked facies"), which correlates with the degree of striatal dopaminergic deficiency, is one of the clinical hallmarks of PD reflecting the severity of hypokinesia and rigidity in the orofacial musculature. In this report, we emphasize the effects of MF on the hypomimia of PD and provide visual documentation illustrating the changes in the patients' facial expression which follow treatment with MF.

摘要

最近有报道称,皮特斯拉级别的磁场(MF)外部应用对帕金森病(PD)患者有效,包括那些出现左旋多巴相关运动障碍的患者。在本报告中,我们介绍另外四名帕金森病患者,他们在接受MF治疗后的短时间内,运动症状有显著改善。其中三名患者在接受MF治疗期间一直在服用抗帕金森病药物,而第四名患者从未接受过药物治疗。磁疗不仅在运动方面(静止性震颤、步态失用、姿势不稳)有改善,在疾病的非运动方面,包括情绪、睡眠、疼痛、厌食、自主神经和认知功能方面也有改善,这证明了皮特斯拉级别的外部MF在治疗帕金森病方面具有独特的疗效。面部表情贫乏(表情减少、“面具脸”)与纹状体多巴胺能缺乏程度相关,是PD的临床特征之一,反映了口面部肌肉运动减少和僵硬的严重程度。在本报告中,我们强调MF对PD表情减少的影响,并提供视觉记录,说明患者面部表情在接受MF治疗后的变化。

相似文献

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Further observations on the unique efficacy of picoTesla range magnetic fields in Parkinson's disease.关于皮特斯拉范围磁场对帕金森病独特疗效的进一步观察。
Int J Neurosci. 1993 Mar-Apr;69(1-4):167-83. doi: 10.3109/00207459309003328.
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Treatment of Parkinson's disease with magnetic fields reduces the requirement for antiparkinsonian medications.用磁场治疗帕金森病可减少抗帕金森病药物的用量。
Int J Neurosci. 1994 Jan-Feb;74(1-4):191-201. doi: 10.3109/00207459408987239.
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Magnetic fields in the therapy of parkinsonism.磁场在帕金森病治疗中的应用
Int J Neurosci. 1992 Oct;66(3-4):209-35.
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Int J Neurosci. 1993 May;70(1-2):85-96. doi: 10.3109/00207459309000564.
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Naltrexone attenuates the antiparkinsonian effects of picoTesla range magnetic fields.纳曲酮减弱了皮特斯拉范围磁场的抗帕金森病作用。
Int J Neurosci. 1994 Sep;78(1-2):111-22. doi: 10.3109/00207459408986050.
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Magnetic fields in the treatment of Parkinson's disease.磁场在帕金森病治疗中的应用
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Weak magnetic fields antagonize the effects of melatonin on blood glucose levels in Parkinson's disease.弱磁场可拮抗褪黑素对帕金森病患者血糖水平的影响。
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Rapid improvement of visuoperceptive functions by picoTesla range magnetic fields in patients with Parkinson's disease.帕金森病患者中皮特斯拉级磁场对视觉感知功能的快速改善
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引用本文的文献

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The Story behind the Mask: A Narrative Review on Hypomimia in Parkinson's Disease.面具背后的故事:帕金森病表情减少的叙述性综述
Brain Sci. 2024 Jan 22;14(1):109. doi: 10.3390/brainsci14010109.