Merle H, Smadja D, Bera O, Cabre P, Vernant J C
Service d'Ophtalmologie, Centre Hospitalier Universitaire de Fort-de-France, Hôpital Pierre-Zobda-Quitman.
J Fr Ophtalmol. 1994;17(6-7):403-13.
We present the results of ophthalmologic examinations of a consecutive series of 30 patients with HTLV-I associated myelopathy. This is the first ophthalmologic prospective study reported outside the Japanese endemic area. Twenty-one of the patients (70%) had kerato-conjunctivitis sicca in addition to accessory salivary gland lymphocytary infiltration in 7. Two cases of uveo-papillitis, 1 case of cotton-wool spots and 3 cases of retinochoroidal degeneration were also observed. Moreover, an aliquot of the aqueous humour was collected from the anterior chamber in 5 patients and showed high titer of HTLV-I antibodies for the 2 patients with uveo-papillitis. We propose different hypotheses to explain the physiopathologic characteristics of these features.
我们展示了对连续30例成人T细胞白血病病毒I型相关脊髓病患者进行眼科检查的结果。这是日本流行区以外报道的第一项眼科前瞻性研究。21例患者（70%）患有干燥性角结膜炎，7例伴有副唾液腺淋巴细胞浸润。还观察到2例葡萄膜视乳头炎、1例棉絮斑和3例视网膜脉络膜变性。此外，从5例患者的前房采集了一份房水样本，其中2例葡萄膜视乳头炎患者的样本显示成人T细胞白血病病毒I型抗体滴度很高。我们提出了不同的假说来解释这些特征的病理生理特点。
