Schärli A F, Rumlova E
Infusionsther Klin Ernahr. 1975 Feb;2(1):51-5.
After operations in infancy considerable negative nitrogen balances are regularly observed. Balance examinations have demonstrated that there is a minimal requirement of 300 to 350 mg N in the form of a crystalline amino acid solution for the normalization of the catabolic condition of metabolism. The administration of nitrogen, however, is only reasonable, if simultaneously 60 cal/kg of combustible energy is supplied. In severe surgical diseases and in neonates the metabolic requirements can be twice as high. In such cases, if correctly applied and accompanied by controls of the metabolic condition, parenteral nutrition can be useful and may, therefore, be regarded as one of the greatest progresses of modern medicine.
在婴儿期手术后,经常会观察到相当程度的负氮平衡。平衡检查表明,以结晶氨基酸溶液形式存在的氮最低需求量为300至350毫克,才能使分解代谢状态的新陈代谢恢复正常。然而,只有在同时提供60千卡/千克可燃能量的情况下,补充氮才是合理的。在严重的外科疾病和新生儿中,代谢需求可能会高出两倍。在这种情况下,如果正确应用并辅以代谢状况的监测,肠外营养可能会很有用,因此可被视为现代医学最伟大的进步之一。