Poggi R, Polese G, Morandini G C, Rossi A
Respiratory Division, OCM, Italy.
Monaldi Arch Chest Dis. 1994 Jun;49(3 Suppl 1):40-2.
Application of positive and expiratory pressure (PEEP) is widely used in mechanically ventilated patients with acute respiratory failure (ARF) due to adult respiratory distress syndrome. Recent studies have suggested that application of PEEP can be useful in patients with chronic obstructive pulmonary disease (COPD) to reduce the mechanical inspiratory load due to intrinsic positive and expiratory pressure (PEEPi). In any ventilatory mode (controlled mechanical ventilation, assisted mechanical ventilation) and during weaning, application of moderate levels of PEEP replace in part PEEPi without adding to it and without significantly increasing lung volume.
对于因成人呼吸窘迫综合征导致急性呼吸衰竭（ARF）的机械通气患者，应用呼气末正压（PEEP）已被广泛使用。最近的研究表明，对于慢性阻塞性肺疾病（COPD）患者，应用PEEP有助于降低因内源性呼气末正压（PEEPi）所致的机械吸气负荷。在任何通气模式（控制机械通气、辅助机械通气）及撤机过程中，应用适度水平的PEEP可部分替代PEEPi，而不会增加PEEPi且不会显著增加肺容积。
