细胞介导免疫在念珠菌病中的作用。
The role of cell-mediated immunity in candidiasis.
作者信息
Fidel P L, Sobel J D
机构信息
Divn of Infectious Diseases, Wayne State University School of Medicine, Harper Hospital, Detroit, MI 48201.
出版信息
Trends Microbiol. 1994 Jun;2(6):202-6. doi: 10.1016/0966-842x(94)90112-i.
PMID:8087452
Abstract
Clinical observations and animal models show that cell-mediated immunity (CMI) is an important host defense mechanism against Candida albicans infections. In HIV-infected patients, a switch from TH1- to TH2-type CMI responses correlates with the progression to AIDS, and may also increase susceptibility to mucosal candidiasis.
摘要
临床观察和动物模型表明，细胞介导的免疫（CMI）是宿主抵御白色念珠菌感染的重要防御机制。在HIV感染患者中，从TH1型向TH2型CMI反应的转变与艾滋病的进展相关，也可能增加黏膜念珠菌病的易感性。
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