Ito M, Hayashi K, Yamada M, Nakamura T
Department of Radiology, Nagasaki University School of Medicine, Japan.
Br J Radiol. 1994 Aug;67(800):759-63. doi: 10.1259/0007-1285-67-800-759.
We measured the vertebral heights and spinal bone mineral density (BMD) of healthy women, and morphometrically evaluated the physiological features of the vertebrae to investigate the relationship of BMD to types of spinal deformity as well as the radiographic detection rate for decreased vertebral bone density. Vertebral BMD was measured from L1 to L4 using dual X-ray absorptiometry and from L1 to L3 using quantitative computed tomography in 245 healthy women ranging in age from 22 to 81 years. The vertebral heights, anterior (Ha), middle (Hm), and posterior (Hp), were measured from T12 through L5, and the Ha/Hp and Hm/Hp ratios were calculated. Although the age-related reduction of vertebral height was not as marked as that of BMD, the vertebral heights, especially the Ha and Hm from T12 to L5 vertebrae, and the Ha/Hp and Hm/Hp from T12 to L3, significantly decreased with age. The presence of a wedge-shaped deformity was strongly related to cortical BMD, and biconcave deformity to trabecular BMD. Although investigation of the sensitivity and specificity of several criteria revealed that vertebra-specific dimension criteria are useful in the detection of decreased bone density, the detection of decreased BMD using vertebral measurements is considered to be limited.
我们测量了健康女性的椎体高度和脊柱骨密度（BMD），并从形态学上评估了椎体的生理特征，以研究骨密度与脊柱畸形类型的关系以及椎体骨密度降低的影像学检测率。对245名年龄在22至81岁之间的健康女性，使用双能X线吸收法测量L1至L4椎体的骨密度，使用定量计算机断层扫描测量L1至L3椎体的骨密度。测量了从T12到L5椎体的高度，包括前部（Ha）、中部（Hm）和后部（Hp），并计算了Ha/Hp和Hm/Hp比值。尽管与年龄相关的椎体高度降低不如骨密度降低明显，但从T12到L5椎体的高度，尤其是Ha和Hm，以及从T12到L3的Ha/Hp和Hm/Hp，均随年龄显著降低。楔形畸形的存在与皮质骨密度密切相关，双凹畸形与小梁骨密度密切相关。尽管对几种标准的敏感性和特异性进行研究发现，特定椎体尺寸标准在检测骨密度降低方面很有用，但使用椎体测量来检测骨密度降低被认为是有限的。
