Veltri A, Capello S, Faissola B, Spalluto F, Farinet S, Grosso M
Istituto di Radiologia, Università di Torino, Italy.
Cardiovasc Intervent Radiol. 1994 May-Jun;17(3):133-7. doi: 10.1007/BF00195505.
The goal of the study is to evaluate utility of contrast-enhanced ultrasound (US) with carbon dioxide microbubbles in evaluation of hepatic lesions.
Twenty-eight patients with single or multiple hepatic lesions (11 hepatocellular carcinoma, 8 hemangiomas, 5 metastases, 1 adenoma, 1 focal nodular hyperplasia, 2 regenerative nodules) were examined. US exam was performed during intraarterial injection of 10 ml of CO2 through the same catheter employed for liver arteriography. The US exam was videotaped in its salient phases. Characteristics of enhancement were evaluated and correlated with histological findings or patient follow-up.
Sonographic angiography clearly demonstrated vascularization of the lesions. Hepatocellular carcinoma, hemangioma, metastases, focal nodular hyperplasia, and regenerative nodules had very characteristic patterns. The injection of CO2 allowed detection of small additional nodules.
Sonographic angiography can improve characterization and staging of hepatic tumors. Low cost and the simplicity of the technique should encourage further experimentation.
本研究的目的是评估二氧化碳微泡增强超声（US）在评估肝脏病变中的效用。
对28例有单个或多个肝脏病变的患者（11例肝细胞癌、8例血管瘤、5例转移瘤、1例腺瘤、1例局灶性结节性增生、2例再生结节）进行检查。通过用于肝脏血管造影的同一导管在动脉内注射10 ml二氧化碳期间进行超声检查。超声检查在其显著阶段进行录像。评估增强特征并与组织学结果或患者随访情况相关联。
超声血管造影清楚地显示了病变的血管化。肝细胞癌、血管瘤、转移瘤、局灶性结节性增生和再生结节具有非常典型的模式。注射二氧化碳能够检测到额外的小结节。
超声血管造影可改善肝脏肿瘤的特征描述和分期。该技术成本低且操作简单，应鼓励进一步试验。
