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洗必泰(0.12%)冲洗对拔牙后牙周组织愈合的影响。(I)临床参数。

Effect of chlorhexidine (0.12%) rinses on periodontal tissue healing after tooth extraction. (I). Clinical parameters.

作者信息

Lang N P, Schild U, Brägger U

机构信息

University of Berne, School of Dental Medicine, Switzerland.

出版信息

J Clin Periodontol. 1994 Jul;21(6):415-21. doi: 10.1111/j.1600-051x.1994.tb00739.x.

Abstract

The aim of the present study was to evaluate the effects of a 1-month period of chlorhexidine (CHX) rinses on the periodontal conditions of teeth adjacent to extraction sockets. 40 patients signed consent forms for this double blind trial and were randomly assigned to either the test group rinsing 2 x daily with 15 ml of a 0.12% CHX solution (Peridex) starting 2 days after tooth extraction or the control group rinsing with a placebo solution for 30 days. Clinical periodontal parameters were obtained from test sites located adjacent to as well as matched controls distant to the extraction sites. The measurements were performed at baseline before the extraction and 1, 2, 3 and 6 months thereafter. During the observation period, the patients were exposed to initial periodontal therapy. The test sites of the group rinsing with CHX demonstrated significantly reduced (p < 0.05) plaque indices, gingival indices and lower %s of sites bleeding on probing one month following the extraction. The test sites of the control group rinsing with the placebo demonstrated a tendency for loss of clinical attachment between 1 and 2 months after the tooth extraction. The mean pocket probing depth (PPD) at test sites of the CHX rinsing group was smaller than in the placebo rinsing group at the one month examination. Also, the mean PPD of the test sites in the CHX group was significantly smaller than at the control sites at 1 month. This difference was not observed in the control group rinsing with placebo.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

本研究的目的是评估为期1个月的洗必泰(CHX)冲洗对拔牙窝相邻牙齿牙周状况的影响。40名患者签署了该双盲试验的同意书,并被随机分配到试验组或对照组。试验组在拔牙后2天开始每天用15毫升0.12%的CHX溶液(派丽奥)冲洗2次,对照组用安慰剂溶液冲洗30天。临床牙周参数取自拔牙部位相邻的试验部位以及与之匹配的对照部位。测量在拔牙前的基线以及拔牙后1、2、3和6个月进行。在观察期内,患者接受了初始牙周治疗。CHX冲洗组的试验部位在拔牙后1个月时,菌斑指数、牙龈指数显著降低(p<0.05),探诊出血部位百分比更低。对照组用安慰剂冲洗的试验部位在拔牙后1至2个月间有临床附着丧失的趋势。CHX冲洗组试验部位在1个月检查时的平均探诊深度(PPD)小于安慰剂冲洗组。此外,CHX组试验部位的平均PPD在1个月时显著小于对照部位。用安慰剂冲洗的对照组未观察到这种差异。(摘要截选至250字)

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