Yoshikawa T, Yamamoto M, Inaba S, Nagai T, Terai T
First Department of Medicine, Obihiro Kosei Hospital.
Nihon Kyobu Shikkan Gakkai Zasshi. 1994 Jun;32(6):610-5.
Identical twin sisters who developed sarcoidosis at an interval of one year are reported. Case 1. (elder sister) A 22-year-old female was admitted to our hospital for examination of cervical lymph node swelling. Her chest roentgenogram showed bilateral hilar lymphadenopathy and the diagnosis was confirmed histologically by scalene node biopsy. Case 2. (younger sister) In 1987, at age 23, a routine chest roentgenogram showed bilateral hilar lymphadenopathy and the diagnosis was confirmed histologically by transbronchial lung biopsy. The occurrence of sarcoidosis in identical twins suggests that a genetic factor might be involved in the pathogenesis.
本文报道了一对同卵双胞胎姐妹，她们先后间隔一年患结节病。病例1（姐姐）：一名22岁女性因颈部淋巴结肿大入院检查。胸部X线片显示双侧肺门淋巴结肿大，经斜角肌淋巴结活检组织学确诊。病例2（妹妹）：1987年，23岁时，常规胸部X线片显示双侧肺门淋巴结肿大，经支气管肺活检组织学确诊。同卵双胞胎患结节病提示遗传因素可能参与了发病机制。
