Yakoleff-Greenhouse V, Flisser A, Sierra A, Larralde C
J Parasitol. 1982 Feb;68(1):39-47.
By studying the reactions and cross-reactions of antigen extracts from different collections of Taenia solium with their respective hyperimmune antisera, and by using numerical taxonomy to analyze the results, a measure of antigenic diversification within T. solium was established. Results varied somewhat depending on the immunological method employed. Double immunodiffusion and immunoelectrophoresis agreed in that all cysticerci were not identical, but shared approximately one third of their antigens. Double immunodiffusion recognized two groups of identical cysticerci: one included 50% of the cysticerci and the other, 21%. Immunoelectrophoresis was more discriminatory in that it recognized few extracts as identical. Electrophoretic data revealed that the most frequently shared antigen among cysticerci corresponded to that most frequently detected by immunologically responsive humans with cerebral cysticercosis. Antigen diversification of T. solium may provide a possible explanation of the pleomorphic immune response of man to this parasite.U
通过研究来自不同猪带绦虫样本的抗原提取物与其各自的超免疫抗血清之间的反应和交叉反应，并使用数值分类法分析结果，确定了猪带绦虫内部抗原多样化的程度。结果因所采用的免疫方法而略有不同。双向免疫扩散和免疫电泳的结果一致表明，所有囊尾蚴并非完全相同，但约有三分之一的抗原是共享的。双向免疫扩散识别出两组相同的囊尾蚴：一组包含50%的囊尾蚴，另一组包含21%。免疫电泳的区分能力更强，因为它识别出很少有提取物是相同的。电泳数据显示，囊尾蚴之间最常共享的抗原与脑囊尾蚴病免疫反应人群中最常检测到的抗原相对应。猪带绦虫的抗原多样化可能为人对这种寄生虫的多形免疫反应提供一种可能的解释。
