一种针对婴儿利什曼原虫感染巨噬细胞的犬CD8 + 细胞毒性T细胞系。 - Suppr

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超能文献

A canine CD8+ cytotoxic T-cell line specific for Leishmania infantum-infected macrophages.

作者信息

Pinelli E, Boog C J, Rutten V P, van Dijk B, Bernadina W E, Ruitenberg E J

机构信息

Department of Immunology, Faculty of Veterinary Medicine, Utrecht, The Netherlands.

出版信息

Tissue Antigens. 1994 Mar;43(3):189-92. doi: 10.1111/j.1399-0039.1994.tb02321.x.

DOI:10.1111/j.1399-0039.1994.tb02321.x

PMID:8091417

Abstract

摘要

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A canine CD8+ cytotoxic T-cell line specific for Leishmania infantum-infected macrophages.一种针对婴儿利什曼原虫感染巨噬细胞的犬CD8 + 细胞毒性T细胞系。

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Dogs vaccinated with gentamicin-attenuated Leishmania infantum or infected with wild-type parasite can be distinguished by Western blotting.经庆大霉素减毒的利什曼原虫或野生型寄生虫感染的狗可通过 Western blot 区分。

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T lymphocytes and macrophages in the intestinal tissues of dogs infected with Leishmania infantum.感染婴儿利什曼原虫的犬肠道组织中的T淋巴细胞和巨噬细胞。

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LBSapSal-vaccinated dogs exhibit increased circulating T-lymphocyte subsets (CD4⁺ and CD8⁺) as well as a reduction of parasitism after challenge with Leishmania infantum plus salivary gland of Lutzomyia longipalpis.接种LBSapSal的犬只在感染婴儿利什曼原虫加长须罗蛉唾液腺后，循环T淋巴细胞亚群（CD4⁺和CD8⁺）增加，寄生虫感染减少。

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