Shayne P, Hart A
Department of Emergency Medicine, Cook County Hospital, Chicago, Illinois.
Ann Emerg Med. 1994 Oct;24(4):736-40. doi: 10.1016/s0196-0644(94)70286-1.
Thyrotoxic periodic paralysis (TPP) is an uncommon syndrome that can be fatal. We report the case of a patient with acute, severe muscle weakness and hypokalemia who was diagnosed in the emergency department to have thyrotoxicosis with acute TPP. The hypokalemia was treated aggressively with potassium without effect. After administration of i.v. propranolol, the patient had complete resolution of symptoms, with mild rebound hyperkalemia. The literature on the use of propranolol in TPP is reviewed, and the known pathophysiology of TPP is discussed.
甲状腺毒症性周期性瘫痪（TPP）是一种罕见且可能致命的综合征。我们报告了一例在急诊科被诊断为甲状腺毒症合并急性TPP的患者，该患者出现急性、严重的肌肉无力和低钾血症。低钾血症经积极补钾治疗无效。静脉注射普萘洛尔后，患者症状完全缓解，伴有轻度反弹性高钾血症。本文回顾了普萘洛尔在TPP中的应用文献，并讨论了TPP已知的病理生理学。
