Collet E, Lacroix M, Dalac S, Ponnelle C, Lambert D
Service de Dermatologie, Hôpital du Bocage, Dijon.
Ann Dermatol Venereol. 1994;121(1):21-4.
Allergic contact dermatitis to gold and its alloys is a rare affection and it is difficult to interpret gold salts patch tests. We report two cases of patients with positive patch tests to 0.5% sodium aurothiosulfate discovered during a dermatology exploration of an occupational contact eczema (for the first patient) and an intolerance to gold jewelry (for the second). There is much confusion in the literature concerning the allergologic exploration of contact dermatitis to gold: no standardized test, possible cross reactions between different gold salts, the tests often irritate. The mechanism of sensitization to gold salts is unknown since pure gold is inalterable and does not contain any salts. The pertinence of a positive test to one or more gold salts must therefore be examined carefully and the diagnosis of gold allergy must not be made without sufficient evidence.
对金及其合金的过敏性接触性皮炎是一种罕见病症，金盐斑贴试验结果难以解读。我们报告两例患者，第一例患者在职业性接触性湿疹的皮肤科检查中，第二例患者在对金首饰不耐受的检查中，斑贴试验对0.5%硫代硫酸金钠呈阳性。关于金接触性皮炎的变应性检查，文献中存在诸多混淆之处：没有标准化试验，不同金盐之间可能存在交叉反应，试验常常会引起刺激。由于纯金性质稳定且不含任何盐类，因此金盐致敏机制尚不清楚。所以，必须仔细检查对一种或多种金盐的阳性试验的相关性，没有充分证据时不得诊断为金过敏。
