Chen Jennifer K, Lampel Heather P
From the *Department of Dermatology, Stanford University, CA; and †Department of Dermatology, Duke University, Durham, NC.
Dermatitis. 2015 Mar-Apr;26(2):69-77. doi: 10.1097/DER.0000000000000101.
In 2001, gold was named Contact Allergen of the Year. More than a decade later, we continue to face several challenges in defining the role of gold in contact allergy. First, interpretation of gold reactions in the setting of epicutaneous patch testing may be difficult; in addition to being a common irritant, gold may be associated with significantly delayed and persistent reactions. Second, although gold compounds are commonly positive on patch testing, clinical relevance is relatively low and may be challenging to determine. Third, the complex interplay between gold and the human body is still poorly understood. In this review, we provide an overview of the literature concerning gold patch test positivity and present recommendations for epicutaneous patch testing with gold.
2001年，金被评为年度接触性变应原。十多年后，我们在界定金在接触性过敏中的作用方面仍面临若干挑战。首先，在进行表皮斑贴试验时，对金反应的解读可能存在困难；除了是一种常见的刺激物外，金还可能与显著延迟和持续的反应有关。其次，尽管金化合物在斑贴试验中通常呈阳性，但临床相关性相对较低，可能难以确定。第三，金与人体之间复杂的相互作用仍知之甚少。在本综述中，我们概述了有关金斑贴试验阳性的文献，并提出了金表皮斑贴试验的建议。
