脑脊液髓鞘碱性蛋白与多发性硬化症
Cerebrospinal fluid myelin basic protein and multiple sclerosis.
作者信息
Cohen S R, Brune M J, Herndon R M, McKhann G M
出版信息
Adv Exp Med Biol. 1978;100:513-9. doi: 10.1007/978-1-4684-2514-7_37.
PMID:80949
Abstract
We have previously reported that myelin basic protein appears in CSF during acute attacks of multiple sclerosis. These studies have been extended to over 700 patients, 91 with multiple sclerosis. The data continues to indicate that myelin basic protein is released into cerebrospinal fluid during acute attacks of multiple sclerosis. We are currently characterizing the basic protein in the CSF.
摘要
我们之前曾报道过，在多发性硬化症急性发作期间，髓鞘碱性蛋白会出现在脑脊液中。这些研究已扩展至700多名患者，其中91名患有多发性硬化症。数据继续表明，在多发性硬化症急性发作期间，髓鞘碱性蛋白会释放到脑脊液中。我们目前正在对脑脊液中的碱性蛋白进行特性描述。
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